QOL {TrialSize} | R Documentation |
Under the time series model, determine sample size based on normal approximation.
QOL(alpha, beta, c, epsilon)
alpha |
significance level |
beta |
power = 1-beta |
c |
constant c=0.5 |
epsilon |
a meaningful difference epsilon. If the chosen acceptable limits are (-δ, δ). epsilon=δ-η, η is the measure for detecting an equivalence when the true difference in treatment means is less than a small constant η. |
Chow SC, Shao J, Wang H. Sample Size Calculation in Clinical Research. New York: Marcel Dekker, 2003
Example.15.4.3<-QOL(0.05,0.1,0.5,0.25) Example.15.4.3