Dose.Response.binary {TrialSize} | R Documentation |
pi is the proportion of response in the ith group.
Ho: p1=p2=...=pk
Ha: L(p)= ∑ ci \times pi = ε, not equal to 0
Dose.Response.binary(alpha, beta, pi, ci, fi)
alpha |
significance level |
beta |
power = 1-beta |
pi |
pi is the proportion of response in the ith group. |
ci |
a linear contrast coefficients ci with ∑ ci=0 . |
fi |
fi=ni/n is the sample size fraction for the ith group |
Chow SC, Shao J, Wang H. Sample Size Calculation in Clinical Research. New York: Marcel Dekker, 2003
pi=c(0.05,0.12,0.14,0.16); ci=c(-6,1,2,3); Example.11.2<-Dose.Response.binary(alpha=0.05,beta=0.2,pi=pi,ci=ci,fi=1/4) Example.11.2 #382